Sr. Dir, Biology-Discovery Job at Merck, Bent County, CO

  • Merck
  • Bent County, CO

Job Description

Merck seeks a senior scientific leader to oversee translational research and biomarker strategy for immunology programs. The role involves leading cross-functional teams, designing hypothesis-driven studies, and bridging discovery with early clinical development to advance immune-focused therapeutics.

Responsibilities

  • Lead and mentor translational and biomarker research teams while setting scientific direction and portfolio priorities
  • Design and execute translational experimental plans including in vitro, ex vivo, and animal model studies aligned with clinical endpoints
  • Oversee biomarker strategy implementation across preclinical and clinical settings with internal and external partners
  • Identify and manage research partnerships with academic investigators and CROs for patient sample acquisition and multi-omics data generation
  • Champion adoption of emerging technologies and therapeutic modalities to advance novel immunology targets and programs

Requirements

  • Bachelor's degree with 20+ years, Master's with 18+ years, or Ph.D. with 10+ years in immunology or related field
  • At least 7 years of direct pharmaceutical industry experience
  • 5+ years managing multiple teams with demonstrated leadership and talent development
  • Deep knowledge of immune-mediated diseases, molecular pathways, and competitive immunology landscape
  • Experience establishing translational research strategies and developing clinically relevant biomarkers
  • Strong cross-functional collaboration skills with clinical, regulatory, and medical affairs teams

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